Optimizing Perfusion Imaging of pTILT in the Presence of Magnetic Field Inhomogeneity

Introduction Pseudo-continuous transfer insensitive labeling technique (pTILT) is a novel pseudo-continuous arterial spin labeling method, which employs nonadiabatic saturation RF pulses for tagging [1]. However, magnetic field inhomogeneities, can compromise the labeling efficacy of pTILT, which induces loss in SNR and perfusion quantification errors. We propose a method to restore the signal loss by correcting the field inhomogeneity effects. This will provide more robust perfusion measures than the conventional pTILT technique.